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CBD & Gut Health: What’s the Connection?

CBD is a fascinating ingredient that has a connection to the gut. It should be included in a supplement program that supports healthy intestinal function. To really understand why, it is important to first understand a few basics.

The largest interface between an individual and their external environment is the gut, which encompasses all of his intestinal tract. Think about it, the only line of defense is the single-celled gut wall. It protects the bloodstream against various toxins and irritants that end up in the digestive system. It is essential for nearly every aspect of human health, as well as mental health.

The gut functions as a second brain

Because of the direct communication between the brain, gut and brain, the gut is often called “the second mind”. Most people are shocked to learn that 95% of the body’s “feel-good” neurotransmitter, serotonin, is actually made in the gut. The endocannabinoid may be partially responsible for the relationship between these two organs, which is known as the “gut-brain-axis”.

Integrity of the gut wall’s integrity is crucial. A healthy gut lining can be described as a thin layer of tightly woven mesh. It serves a vital function, keeping the toxins and food particles out of the bloodstream.

The bad guys can get away with it if they injure the gut lining

It’s almost like ripping a hole in cheesecloth when there is injury or inflammation to the gut. The bloodstream is now leaking into the body from stuff that isn’t there. This is known as intestinal permeability or leaky gut syndrome. The immune system goes into high alert when errant particles enter the bloodstream. It recognizes foreigners and launches an attack. You get all sorts of symptoms.

These symptoms may include constipation, diarrhea, disruptions in gut motility (the rate at which food moves through your digestive tract), and activation of autoimmune disorders. A general feeling of unwellness is common. Doctors often say, “Treat your gut first” or “Health starts in the gut.”

How does CBD fit into the picture?

CBD plays a significant role in the structure as well as the function of your gut. There are CB-1 and CB-2 receptors in the gut. This further supports the argument for the involvement of the endocannabinoid systems in gut health. These are just a few of the many ways CBD can support gut health.

1. It can affect TNF-alpha production.

CBD has been shown to reduce the production of TNF-alpha. This is a major inflammatory compound that can be released when the gut’s inflammation response is off the track. CBD reduces TNF-alpha production and supports healthy inflammation in the gut.

2.It can affect gut motility.

We also know that gut motility is affected by the endocannabinoid systems. Diarrhea is a common side effect of slow motility If it is too slow, it can lead to constipation. CBD supports healthy gut motility. CBD can assist the body to achieve the “Goldilocks effect” in digestion. It is not too fast or too slow, but just right.

3. Cross-talk exists between the Endocannabinoid System and the gut microbiome.

There is strong evidence that there is “cross-talk” between trillions of beneficial and harmful microbes in your gut (the microbiome) and the endocannabinoid systems. Multiple animal studies have demonstrated that CBD administration has gut-related health benefits. Finally, CBD has been shown to have a positive effect on people with gut issues. While there were no significant differences in the remission rates between the CBD-supplemented and placebo groups, the CBD-supplemented patients experienced more gastrointestinal distress than those who didn’t receive CBD supplementation. According to doctors’ subjective impressions, CBD-supplemented patients experienced significantly better quality-of-life outcomes. This included a decrease in the severity of their illness.

This is all to say, CBD is an important supplement to a regimen that supports the healthy structure of the gut.

This post was written by Flo Sugyatno, operations manager of PureMed and CBD Expert. At PureMed we are a CBD store in Washington DC. We know that the best product comes from the best ingredients. That’s why we only use local, non-GMO ingredients that are grown without pesticides! We Produce Worry-Free CBD. Click here for more information.

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